Purexa™ OdT
for mRNA Purification

A rapid mRNA purification product that utilizes affinity membrane adsorber technologies. This chromatography product offers up to 10x the productivity compared to traditional resins.

How Purexa™ OdT Works

Purexa™ OdT can successfully separate target mRNA species regardless of size. Productivity is enhanced with faster flow rates while providing high purity eluates. Purexa™ OdT paired with our HIC and AEX columns allows for a seamless purification process to isolate mRNA.

Recommended buffers for mRNA purification with Purexa™ OdT

Running Buffer: 50 mM Sodium Phosphate + 250 mM NaCl, pH 7.0
Wash Buffer: 50 mM Sodium Phosphate, pH 7.0
Elution Conditions: Deionized water or 20 mM Tris pH 7.0
Cleaning Solution: 0.1 M NaOH.

Purexa™ OdT
Increase Productivity with Purexa

As shown in Figures 1-4, Purexa™ OdT membrane chromatography provides high binding capacity and short residual time, regardless of the size of the molecule, resulting in up to 10 times faster processing than with resin chromatography.

Purilogics’ membranes can purify
and are not limited to these common biologics :

The Purexa™ product line has pore sizes ranging from 0.3µm to 5 µm. With a much larger pore size, the target molecule is easily able to bind to the membrane at a high capacity, regardless of the size. Thus, Purilogics’ membrane chromatography products can be applied for the purification of many sizes of biologics while also maintaining and a rapid flow rate and high binding capacity.

Monoclonal Antibody
mRNA
Adeno-associated virus (AAV)
Lentivirus/Lentiviral vectors (LV)
Plasmid DNA
Oligo nucleotides; Nucleotides/Nucleosides

Purexa™ OdTfor mRNA Purification

How Purexa™ OdT Works

Recommended buffers for mRNA purification with Purexa™ OdT

Purexa™ OdTIncrease Productivity with Purexa

Purilogics’ membranes can purifyand are not limited to these common biologics :

Purexa™ OdT
for mRNA Purification

Purexa™ OdT
Increase Productivity with Purexa

Purilogics’ membranes can purify
and are not limited to these common biologics :